Toxicology of deoxynivalenol and its acetylated and modified forms

D Payros, I Alassane-Kpembi, A Pierron, N Loiseau… - Archives of …, 2016 - Springer
Mycotoxins are the most frequently occurring natural contaminants in human and animal diet.
Among them, deoxynivalenol (DON), produced by Fusarium, is one of the most prevalent …

[HTML][HTML] Impact of mycotoxin on immune response and consequences for pig health

A Pierron, I Alassane-Kpembi, IP Oswald - Animal Nutrition, 2016 - Elsevier
Mycotoxins are fungal secondary metabolites detected in many agricultural commodities,
especially cereals. Due to their high consumption of cereals, pigs are exposed to these toxins. …

[HTML][HTML] Impact of two mycotoxins deoxynivalenol and fumonisin on pig intestinal health

A Pierron, I Alassane-Kpembi, IP Oswald - Porcine health management, 2016 - Springer
Mycotoxins are secondary metabolites of fungi that grow on a variety of substrates. Due to
their high consumption of cereals and their sensitivity, pigs are highly impacted by the …

Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species

A Riboulet-Chavey, A Pierron, I Durand, J Murdaca… - Diabetes, 2006 - Am Diabetes Assoc
Nonenzymatic glycation is increased in diabetes and leads to elevated levels of advanced
glycation end products (AGEs), which link hyperglycemia to the induction of insulin resistance…

[HTML][HTML] Microbial biotransformation of DON: molecular basis for reduced toxicity

A Pierron, S Mimoun, LS Murate, N Loiseau, Y Lippi… - Scientific reports, 2016 - nature.com
Bacteria are able to de-epoxidize or epimerize deoxynivalenol (DON), a mycotoxin, to
deepoxy-deoxynivalenol (deepoxy-DON or DOM-1) or 3-epi-deoxynivalenol (3-epi-DON), …

Intestinal toxicity of the masked mycotoxin deoxynivalenol-3-β-d-glucoside

A Pierron, S Mimoun, LS Murate, N Loiseau… - Archives of …, 2016 - Springer
Natural food contaminants such as mycotoxins are an important problem for human health.
Deoxynivalenol (DON) is one of the most common mycotoxins detected in cereals and grains…

[HTML][HTML] Post-COVID-19 syndrome: nine months after SARS-CoV-2 infection in a cohort of 354 patients: data from the first wave of COVID-19 in Nord Franche-Comté …

…, M Osman, N Belfeki, L Toko, P Garnier, A Pierron… - Microorganisms, 2021 - mdpi.com
(1) Background. Post-COVID-19 syndrome is defined as the persistence of symptoms after
confirmed SARS-CoV-2 infection. (2) Methods. ANOSVID is an observational retrospective …

[HTML][HTML] Reduced toxicity of 3-epi-deoxynivalenol and de-epoxy-deoxynivalenol through deoxynivalenol bacterial biotransformation: In vivo analysis in piglets

APFL Bracarense, A Pierron, P Pinton, JR Gerez… - Food and chemical …, 2020 - Elsevier
Ingestion of deoxynivalenol (DON), one of the most common mycotoxin contaminants of
cereals, leads to adverse effects for animal and human health. Bacterial biotransformation is a …

NF-kB2 induces senescence bypass in melanoma via a direct transcriptional activation of EZH2

GM De Donatis, EL Pape, A Pierron, Y Cheli, V Hofman… - Oncogene, 2016 - nature.com
Enhancer of Zeste homologue 2 (EZH2) belongs to the polycomb repressive complex 2 and
catalyzes the methylation of histone H3 lysine 27. These pivotal epigenetic marks are …

Olfactory dysfunction in COVID‐19, new insights from a cohort of 353 patients: the ANOSVID study

…, E Bouvier, PY Royer, A Pierron… - Journal of Medical …, 2022 - Wiley Online Library
Olfactory disorders (OD) pathogenesis, underlying conditions, and prognostic in coronavirus
disease 2019 (COVID‐19) remain partially described. ANOSVID is a retrospective study in …