Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma

…, WJ Urba, JW Smith, KA Margolin, JW Mier… - Journal of clinical …, 2005 - ascopubs.org
Purpose The Cytokine Working Group conducted a randomized phase III trial to determine
the value of outpatient interleukin-2 (IL-2) and interferon alfa-2b (IFN) relative to high-dose (…

Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled …

…, R Tomek, NJ Robert, I Gore, JW Smith… - The lancet …, 2017 - thelancet.com
Background ExteNET showed that 1 year of neratinib, an irreversible pan-HER tyrosine
kinase inhibitor, significantly improves 2-year invasive disease-free survival after trastuzumab-…

Isoprenoid hydrocarbons in coal and petroleum

JD Brooks, K Gould, JW Smith - Nature, 1969 - nature.com
THE isoprenoid hydrocarbons, pristane and phyfcane, which occur together in crude oils 1–4
, oil shale 5 and ancient sediments 6 , are presumed to have been formed from chlorophyll …

Anisakis and anisakiasis

JW Smith, R Wootten - Advances in parasitology, 1978 - Elsevier
Publisher Summary This chapter reviews the literature on Anisakis, including use of the
nematode as a biological tag in applied fishery science. The genetic diagnosis of Anisakis is …

Aspects of the biology of the parasitic copepods Lepeophtheirus salmonis and Caligus elongatus on farmed salmonids, and their treatment

R Wootten, JW Smith, EA Needham - Proceedings of the Royal …, 1982 - cambridge.org
The general biology and pathology of Lepeophtheirus salmonis and Caligus elongatus and
the prevention and treatment of such ‘sea-lice’ infestations on farmed salmonids are …

[PDF][PDF] Adjuvant high-dose bolus interleukin-2 for patients with high-risk renal cell carcinoma: a cytokine working group randomized trial

…, CPG Tretter, D McDermott, JW Smith… - Journal of clinical …, 2003 - academia.edu
Adjuvant High-Dose Bolus Interleukin-2 for Patients With High-Risk Renal Cell Carcinoma: A
Cytokine Working Group Randomized Tri Page 1 Adjuvant High-Dose Bolus Interleukin-2 for …

Targeting FGFR with dovitinib (TKI258): preclinical and clinical data in breast cancer

…, SA Hurvitz, N Turner, H Rugo, JW Smith… - Clinical cancer …, 2013 - AACR
Purpose: Fibroblast growth factor receptor 1 (FGFR1) and FGFR2 amplifications are observed
in approximately 10% of breast cancers and are related to poor outcomes. We evaluated …

Microbial origin of Australian coalbed methane

JW Smith, RJ Pallasser - AAPG bulletin, 1996 - pubs.geoscienceworld.org
Bituminous coal seam gases from the Permian Sydney and Bowen basins, Australia, are
characterized by (1) methane/ethane ratios greater than or equal to 1000, (2) δ 13 C and δD …

Granulocyte–macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non–small-cell lung cancer

…, D Sterman, D Jablons, JW Smith… - Journal of the …, 2004 - academic.oup.com
To evaluate the feasibility, safety, and efficacy of vaccination with autologous tumor cells
genetically modified with an adenoviral vector (Ad-GM) to secrete human granulocyte–…

Interleukin 1α increases serum leptin concentrations in humans

…, GC Powers, WG Alvord, JW Smith… - The Journal of …, 1997 - academic.oup.com
Leptin, the protein product of the ob gene, regulates appetite and body weight in animals.
Endotoxin and cytokines, induced by endotoxin, interleukin (IL) 1 and tumor necrosis factor, …