User profiles for J. Galper
Jasmin GalperMedical scientist, The University of Sydney Verified email at sydney.edu.au Cited by 279 |
Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the relationship between lipid metabolism and …
…, SP Georgescu, KL Johnson, D Kong, JB Galper - Stem cell reviews, 2006 - Springer
Human umbilical vein endothelial cells (HUVECs) have played a major role as a model system
for the study of the regulation of endothelial cell function and the role of the endothelium …
for the study of the regulation of endothelial cell function and the role of the endothelium …
The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart
DE Logothetis, Y Kurachi, J Galper, EJ Neer… - Nature, 1987 - nature.com
Subunits ofguanine nucleotide regulatory proteins purified from bovine cerebral cortex were
used to perfuse the intracellular surface of excised patches of chick embryonic atrial cells. …
used to perfuse the intracellular surface of excised patches of chick embryonic atrial cells. …
3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors interfere with angiogenesis by inhibiting the geranylgeranylation of RhoA
…, L Iruela-Arispe, U Begley, D Tang, JB Galper - Circulation …, 2002 - Am Heart Assoc
Angiogenesis is implicated in the pathogenesis of cancer, rheumatoid arthritis, and
atherosclerosis and in the treatment of coronary artery and peripheral vascular disease. Here, …
atherosclerosis and in the treatment of coronary artery and peripheral vascular disease. Here, …
Role of Toll-like receptor 4 in intimal foam cell accumulation in apolipoprotein e–deficient mice
…, KJ Moore, ME Mendelsohn, JB Galper… - … , and vascular biology, 2011 - Am Heart Assoc
Objective— Atherosclerosis encompasses a conspicuously maladaptive inflammatory
response that might involve innate immunity. Here, we compared the role of Toll-like receptor 4 (…
response that might involve innate immunity. Here, we compared the role of Toll-like receptor 4 (…
Lipid pathway dysfunction is prevalent in patients with Parkinson's disease
Many genetic risk factors for Parkinson’s disease have lipid-related functions and lipid-modulating
drugs such as statins may be protective against Parkinson’s disease. Moreover, the …
drugs such as statins may be protective against Parkinson’s disease. Moreover, the …
Cyclin F: a component of an E3 ubiquitin ligase complex with roles in neurodegeneration and cancer
Cyclin F, encoded by CCNF, is the substrate recognition component of the Skp1-Cul1-F-box
E3 ubiquitin ligase complex, SCF cyclin F . E3 ubiquitin ligases play a key role in ubiquitin-…
E3 ubiquitin ligase complex, SCF cyclin F . E3 ubiquitin ligases play a key role in ubiquitin-…
[HTML][HTML] Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations
…, I Khizhnyak, CJ Jagaraj, J Galper… - Molecular …, 2020 - Springer
Background Pathological forms of TAR DNA-binding protein 43 (TDP-43) are present in motor
neurons of almost all amyotrophic lateral sclerosis (ALS) patients, and mutations in TDP-…
neurons of almost all amyotrophic lateral sclerosis (ALS) patients, and mutations in TDP-…
Simvastatin inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice: possible role of ERK
…, KS Moulton, HJ Park, JB Galper - … , and vascular biology, 2009 - Am Heart Assoc
Objective— Abdominal aortic aneurysm (AAA) is a life-threatening disease affecting almost
10% of the population over age 65. Generation of AAAs by infusion of angiotensin (Ang) II in …
10% of the population over age 65. Generation of AAAs by infusion of angiotensin (Ang) II in …
[HTML][HTML] LRRK2 and lipid pathways: implications for Parkinson's disease
Genetic alterations in the LRRK2 gene, encoding leucine-rich repeat kinase 2, are a common
risk factor for Parkinson’s disease. How LRRK2 alterations lead to cell pathology is an …
risk factor for Parkinson’s disease. How LRRK2 alterations lead to cell pathology is an …
Angiotensin II-induced TLR4 mediated abdominal aortic aneurysm in apolipoprotein E knockout mice is dependent on STAT3
Abdominal Aortic Aneurysm (AAA) is a major cause of mortality and morbidity in men over 65
years of age. Male apolipoprotein E knockout (ApoE −/− ) mice infused with angiotensin II (…
years of age. Male apolipoprotein E knockout (ApoE −/− ) mice infused with angiotensin II (…