… Briefly, 6 M trichloroacetic acid (BDH) was added to the platelet lysates to precipitate the
proteins. The samples were then centrifuged at 10 000 x g for 4 min. A portion of the …

Oncogene-induced senescence is a cellular response that may be crucial for protection against
cancer development 1 , 2 , but its investigation has so far been restricted to cultured cells …

Importance Whether people infected with human immunodeficiency virus (HIV) are at an
increased risk of acute myocardial infarction (AMI) compared with uninfected people is not clear…

… mNa 3 VO 4 , 1 μg/ml leupeptin, 1 mm PMSF) accompanied by brief sonication on ice. … (25
mm Tris-HCl at pH 7.5, 10 mm MgCl 2 , 5 mm β-glycerolphosphate, 2 mm DTT, 0.1 mm Na 3 …

… ) and overexpression of Ris1, the product of the ras-induced senescence gene, m-ris1 (Figure
5B) (Barradas … mycin and 2 M gancyclovir. DNA was isolated from double resistant clones …

The INK4a/ARF tumor suppressor locus, a key executor of cellular senescence, is regulated
by members of the Polycomb group (PcG) of transcriptional repressors. Here we show that …

We examined the relation of invasive pneumococcal disease to season, atmospheric conditions,
and the rate of respiratory virus isolation in a community-wide surveillance program in …

Compounds with specific cytotoxic activity in senescent cells, or senolytics, support the causal
involvement of senescence in aging and offer therapeutic interventions. Here we report …

… 1 mmphenylmethylsulfonyl fluoride. Protein lysates (100 μg) were then incubated with 5 μg
of anti-CDK2 (M-… (20 mm Tris-HCl (pH 8.0), 10 mm MgCl 2 , 1 mm EDTA, 1 mm dithiothreitol), …

… W; 354 m above msl) and millet at the laboratory near Mitchell (40 57' N 103 41' W; 1,225 m
… instrumentation was at least 125 to 150 m. During these studies the height of the sorghum …