[PDF][PDF] Characterization and Wear studies on Non-Asbestos Organic fiber reinforced low metallic friction composites

PE Anbunathan, G Perumal… - International Journal of …, 2019 - researchgate.net
In this work, characterization of Non-Asbestos Organic (NAO) friction composite material was
fabricated by reinforcing organic fibers and low metallic friction materials with the sole aim …

Early serum changes in severely malnourished children with corneal xerophthalmia after injection of water-miscible vitamin A

A Pirie, P Anbunathan - The American Journal of Clinical Nutrition, 1981 - Elsevier
We have studied the response of malnourished, xerophthalmic children to injections of water-miscible
vitamin A to assess the most effective dose. Total dose injected was either greater …

Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma

JW Harbour, EDO Roberson, H Anbunathan… - Nature …, 2013 - nature.com
… as younger patient age (P = 0.03) and fewer undifferentiated epithelioid cells (P = 0.003), …
transcriptome signature (P = 0.02), loss of chromosome 3 (P = 0.001) and mutation of BAP1 (…

Driver mutations in uveal melanoma: associations with gene expression profile and patient outcomes

CL Decatur, E Ong, N Garg, H Anbunathan… - JAMA …, 2016 - jamanetwork.com
… (P = .03 for both). SF3B1 mutations were associated with younger patient age (P = .006). …
absence of ciliary body involvement (P = .008) and greater largest basal diameter (P = .04). …

CARD14 alterations in Tunisian patients with psoriasis and further characterization in European cohorts

…, S Kouidhi, I Zaraa, H Anbunathan… - British Journal of …, 2016 - academic.oup.com
… Arg62Glu (CGG to CAG) variant in a child with GPP who harboured the allele encoding p.Glu138Ala.4
The p.Arg62Glu variant had been inherited from her unaffected father, and it is …

Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

…, KR Parker, E Sotillo, RC Lynn, H Anbunathan… - Science, 2021 - science.org
INTRODUCTION More than 50% of patients treated with chimeric antigen receptor (CAR)–T
cells for B cell malignancies develop progressive disease after CAR therapy, and these …

[PDF][PDF] GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity

…, IS Fetahu, M Hasselblatt, KR Parker, H Anbunathan… - Cancer Cell, 2022 - cell.com
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally
that could serve as immune targets. We developed T cells expressing chimeric antigen …

Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer

…, L Iommarini, H Anbunathan… - … journal of cancer, 2018 - Wiley Online Library
… In the thyroid FRTL-5 cell model stably expressing the mutant MYO1F p.Gly134Ser protein,
… , since we demonstrated that the mutant MYO1F p.Gly134Ser, when overexpressed, can …

Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy

…, J Altreuter, Y Liu, A Jhaveri, V Duong, H Anbunathan… - Cancer Cell, 2024 - cell.com
Chimeric antigen receptor T cells (CAR-Ts) have remarkable efficacy in liquid tumors, but
limited responses in solid tumors. We conducted a Phase I trial (NCT02107963) of GD2 CAR-…

c-Jun overexpression in CAR T cells induces exhaustion resistance

…, E Sotillo, D Gennert, P Xu, Z Good, H Anbunathan… - Nature, 2019 - nature.com
Chimeric antigen receptor (CAR) T cells mediate anti-tumour effects in a small subset of
patients with cancer 1 , 2 – 3 , but dysfunction due to T cell exhaustion is an important barrier to …