Role of MRP4 and MRP5 in biology and chemotherapy

…, M Adachi, S Hatse, L Naesens, J Balzarini, R Flatley… - AAPS PharmSci, 2002 - Springer
Nucleotide efflux (especially cyclic nucleotides) from a variety of mammalian tissues, bacteria,
and lower eukaryotes has been studied for several decades. However, the molecular …

The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and …

JR Whetstine, RM Flatley, LH Matherly - Biochemical Journal, 2002 - portlandpress.com
Our previous study identified two alternate non-coding upstream exons (A and B) in the
human reduced folate carrier (hRFC) gene, each controlled by a separate promoter. Each …

Single Nucleotide Polymorphisms in the Human Reduced Folate Carrier: Characterization of a High-Frequency G/A Variant at Position 80 and Transport Properties of the His27 …

JR Whetstine, AJ Gifford, T Witt, XY Liu, RM Flatley… - Clinical Cancer …, 2001 - AACR
The presence of sequence variants in the human reduced folate carrier (hRFC) was assessed
in leukemia blasts from children with acute lymphoblastic leukemia (ALL) and in normal …

[HTML][HTML] Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing

…, J Sampath, L Lan, D Sun, P Hargrove, R Flatley… - Journal of biological …, 2002 - ASBMB
The multidrug resistance protein MRP4, a member of the ATP-binding cassette superfamily,
confers resistance to purine-based antiretroviral agents. However, the antiviral agent …

[PDF][PDF] Guidelines on the diagnosis and management of Waldenström macroglobulinaemia

RG Owen, G Pratt, RL Auer, R Flatley, C Kyriakou… - Br J …, 2014 - rareconnect.org
… 3 Rituximab + cyclophosphamide + doxorubicin + vincristine + prednisolone (CHOP-R)
should not be used as primary therapy in WM (Grade B1). 4 Chlorambucil remains suitable …

The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines

Y Ge, TL Jensen, ML Stout, RM Flatley, PJ Grohar… - Cancer research, 2004 - AACR
Myeloblasts from Down syndrome (DS) children with acute myeloid leukemia (AML) are
significantly more sensitive in vitro to 1-β-d-arabinofuranosylcytosine (ara-C) and generate …

Soft error considerations for deep-submicron CMOS circuit applications

…, N Leland, D Moyer, S Butler, R Flatley - … Digest (Cat. No …, 1999 - ieeexplore.ieee.org
The increasing importance of characterizing both memory arrays and core logic when estimating
soft error FIT (failure in time) rates has been demonstrated using test-circuits, a 21264 …

Perspectives On... Professional development opportunities for new academic librarians

RK Flatley, MA Weber - The journal of academic librarianship, 2004 - Elsevier
This paper outlines professional development activities for new academic librarians. The
authors review and critique various professional development activities including publishing, …

Librarians and mandatory academic advising at a mid-sized public university: A case study

R Flatley, MA Weber, S Czerny, S Pham - The Journal of academic …, 2013 - Elsevier
This article provides a case study of librarians being assigned the responsibility of providing
academic advising to undeclared students at a mid-sized public university. The experience …

Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter

…, JR Whetstine, SG Payton, Y Ge, RM Flatley… - Biochemical …, 2004 - portlandpress.com
The hRFC (human reduced folate carrier) is ubiquitously but differentially expressed in human
tissues and its levels are regulated by up to seven non-coding regions (A1, A2, A, B, C, D …